The pick of the six games is on the South coast as rivals Solent and Worthing do battle once more, whilst the clash between Hemel and Derby is sure to be frightfully entertaining.
We take a look at all the weekend's games below, with links to live stats and live streams at the bottom of the page.
Two of the league's four remaining unbeaten teams go head-to-head tomorrow as local rivals Worthing Thunder and Team Solent Kestrels face off.
The reigning champions handed out another heavy defeat in week four as they dismantled Newcastle 104-82. Playing without the 'King' Travis Charles, Solent instead turned to an inspired Luke Busumbru who earned his fourth Team of the Week selection.
Thunder go into tomorrow off the back of a strong second half performance over Leicester Warriors to keep their perfect record intact. Hafeez Abdul was the star in that one (24pts, 11reb, 1ast, 1stl, 28eff), also playing his way into the Week four TOTW.
It has all the makings of a classic, and if it's anything like last March's L Lynch Trophy semi-final with Andre Arissol's buzzer beater for Solent (82-80) then NBL fans are in for a treat.
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The weekend begins with Leicester Warriors' (0-4) trip to Thames Valley Cavaliers (2-2). The hosts are still looking for their first W of the season but there were certainly some promising signs in the defeat to Thunder, even leading at half time in last week's encounter. Cavs, meanwhile, will look to build on their huge home win over Bradford last time out.
Team Newcastle University (1-3) travel to Oaklands Wolves (1-3) with similar records and both struggling for points. Ronald Blain's form will be a worry for the hosts, with Newcastle's star man currently averaging 29.5ppg and 10.5rpg.
London Lions II (3-1) are ticking along nicely and come up next against strugglers Essex Rebels (0-4). Rebels haven't been at their best so far this season, sporting a -140 points differential. Another week, another star to contend with for the former D2 South winners, as Lions' Bradley Kaboza scored 26 points off the bench last week and will be looking for more of the same here.
Can Taylor Johnson be stopped? That's the difficult question Derby Trailblazers (2-2) face as they hit the road to unbeaten Hemel Storm (4-0). The American is racking up the Player and Team of the Week awards since the move to his new team this summer, making it three in a row after a 37 point outing last weekend.
The job of toppling Taylor and Hemel won't be made any easier with the news this week that Sol Rolls-Tyson has also left DTB. Averaging 12 points and 6.3 rebounds across three D1M games, coach Shaw's team found a new gear in his absence to hand Nottingham their first defeat of the season last night, coming out on top 94-72 in the L Lynch Trophy quarter-final.
Sunday's only game sees Reading Rockets (2-2) host Loughborough Riders (1-3), with Will Maynard on the hunt for his first W in the Riders hot-seat.
Maynard has recently taken over from Mark Jarram, the Riders' long time coach, who recently moved on to pastures new.
Reading will be happy to spoil the party however as they look to bounce back from last weekend's narrow 81-78 loss to Nottingham Hoods.
3pm - Leicester Warriors v Thames Valley Cavaliers - LIVE STATS/LIVE STREAM
3pm - Oaklands Wolves v Team Newcastle University - LIVE STATS
4pm - London Lions II v Essex Rebels - LIVE STATS/LIVE STREAM
6pm - Team Solent Kestrels v Worthing Thunder - LIVE STATS/LIVE STREAM
7pm - Hemel Storm v Derby Trailblazers - LIVE STATS
5pm - Reading Rockets v Loughborough Riders - LIVE STATS/LIVE STREAM
Main image credit - Luke Simcock